Table 2.
Comparison of left ventricular mechanics between control and sickle cell groups.
| Characteristic | Mean ± SD |
p-value |
||||
|---|---|---|---|---|---|---|
| Control group (20) | Sickle cell (32) |
Control (20) vs. |
Control (20) vs. |
Sickle cell: |
||
| During Crisis (32)c | During follow up (18) | During crisis (32)a | During follow up (18)a | During Crisis (32) vs. During follow up (18)b | ||
| Longitudinal strain | ||||||
| Subendocardial (%) | −20.17 ± 5.48 | −16.40 ± 4.78 | −19.04 ± 1.98 | <0.05** | 0.422 | <0.05** |
| Subepicardial (%) | −17.68 ± 4.95 | −19.13 ± 6.59 | −18.80 ± 4.05 | 0.477 | 0.474 | 0.679 |
| Circumferential strain | ||||||
| Subendocardial (%) | −23.98 ± 8.08 | −21.02 ± 5.43 | −20.74 ± 4.07 | 0.214 | 0.143 | 0.622 |
| Subepicardial (%) | −6.47 ± 1.80 | −14.85 ± 4.54 | −11.74 ± 2.81 | <0.001* | <0.001* | <0.001** |
| Radial (%) | 21.97 ± 10.37 | 41.86 ± 22.27 | 27.11 ± 5.98 | <0.001* | 0.082 | <0.001** |
*p < 0.0001; **p < 0.05.
a
Statistical significance tested at 5% level using t-test for independent samples.
b
Statistical significance tested at 5% level using paired t-test.
c
Includes same cases as appearing in follow up.