Table 4.
Characteristics of patients with fQRS with (group 1) and without (group 2) significant systolic dyssynchrony.
| Characteristic | Group 1 (with systolic dyssynchrony) (n = 39) | Group 2 (no systolic dyssynchrony) (n = 11) | Chi square value | p value |
|---|---|---|---|---|
| Age (in years) | 46.13 ± 14.24 | 45.00 ± 12.20 | 0.80 | |
| Sex (M:F) | 23:16 | 9:2 | 0.43 | 0.51 |
| NYHA class n (%) | 2.74 | 0.09 | ||
| II | 23 (59%) | 4 (57%) | ||
| III-IV | 16 (41%) | 7 (43%) | ||
| Heart rate (BPM) | 91.67 ± 17.74 | 98.09 ± 14.91 | 0.24 | |
| PR interval (ms) | 148.59 ± 29.52 | 155.82 ± 31.49 | 0.51 | |
| QRS duration (ms) | 99.08 ± 13.32 | 100.64 ± 12.62 | 0.72 | |
| LVEF % (Simpson's) | 22.31 ± 5.30 | 22.00 ± 4.43 | 0.85 | |
| EPSS (mm) | 20.47 ± 3.44 | 21.33 ± 1.70 | 0.26 | |
| MR regurgitant volume (ml) | 31.61 ± 13.45 | 30.66 ± 22.41 | 0.90 | |
| TR jet gradient (mm Hg) | 27.09 ± 9.40 | 31.10 ± 7.46 | 0.18 | |
| Mitral E/A | 2.29 ± 1.39 | 3.03 ± 1.70 | 0.21 | |
| IVRT (ms) | 105.23 ± 20.36 | 72.00 ± 8.90 | <0.001* | |
| Septal s (cm/sec) | 2.87 ± 0.81 | 2.93 ± 0.65 | 0.81 | |
| Septal e (cm/sec) | 2.99 ± 1.12 | 2.97 ± 1.04 | 0.97 | |
| Septal a (cm/sec) | 3.84 ± 0.96 | 3.69 ± 1.21 | 0.71 | |
| Lateral s (cm/sec) | 2.94 ± 0.81 | 2.55 ± 0.48 | 0.06 | |
| Lateral e (cm/sec) | 5.01 ± 1.59 | 4.71 ± 2.05 | 0.66 | |
| Lateral a (cm/sec) | 3.21 ± 0.98 | 2.81 ± 1.05 | 0.27 | |
| E/e septal | 32.46 ± 16.97 | 38.08 ± 20.32 | 0.42 | |
| E/e lateral | 20.28 ± 14.43 | 27.05 ± 17.68 | 0.26 | |
| Ts-SD (ms) | 41.67 ± 5.96 | 14.25 ± 4.63 | <0.001* |
Data are as mean ± SD for continuous variable and absolute no. (%) for categorical variable; A-Late diastolic velocity; a-Tissue Doppler imaging late diastolic velocity; E-Early diastolic velocity; EPSS-E point septal separation; e-Tissue Doppler imaging early diastolic velocity; IVRT-Isovolumetric relaxation time; LVEF-Left ventricular ejection fraction; MR-Mitral regurgitation; NYHA-New York Heart Association functional classification; s-Tissue Doppler imaging systolic velocity; TR-Tricuspid regurgitation; Ts-SD-Standard deviation of time to peak systolic velocity of 12 LV segments. *Statistically significant difference in values between two groups.