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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Pharmacogenomics. 2013 Sep;14(12):10.2217/pgs.13.131. doi: 10.2217/pgs.13.131

Figure 2. SNPs in RRM2.

Figure 2

(A) Snapshot from the UCSC genome browser [NCBI/hg18 (2006)] for the RRM2 locus. The regions sequenced in HapMap panels are shown by small boxes. (B) Linkage disequilibrium plot of RRM2 gene in European (CEU) and African (YRI) ancestry samples generated in Haploview using genotype data from the present study and from HapMap for both CEU and YRI samples 20 kb upstream to 5 kb downstream. (C) SNPs that are linked, r2 ≥ 0.75 in CEU and r2 ≥ 0.8 in YRI (and picked by the tagger program), are categorized in the same groups. SNPs located upstream of the translation start site (ATG) are denoted by an asterisk. SNPs without rs numbers are indicated by number corresponding to Table 1.

CEU: Utah residents with northern and western European ancestry; MAF: Minimum allele frequency; YRI: Yoruba people in Ibadan, Nigeria.