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. Author manuscript; available in PMC: 2013 Dec 12.
Published in final edited form as: Oncogene. 2001 Feb 1;20(5):10.1038/sj.onc.1204133. doi: 10.1038/sj.onc.1204133

Fig. 5. PDGF-C expression in EFT cell lines is dependent on EWS/FLI activity.

Fig. 5

A northern blot containing total RNA from polyclonal, continuously selected populations of TC71 and TTC466 cells stably expressing either Δ22, a dominant negative EWS/FLI, or vector alone was probed with human PDGF-C. In both cell lines, blocking EWS/FLI activity with Δ22 decreases PDGF-C transcript levels. TC71 expresses EWS/FLI and TTC466 expresses EWS/ERG. Abundant levels of Δ22 transcript were detected (data not shown).