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Total (A) and acetylated (B) forms of plasma high mobility group box 1 (HMGB1) protein were measured after galactosamine/endotoxin (Gal/End) treatment, bile duct ligation (BDL) or sham-operation. C. Percentage of acHMGB1 compared to the total HMGB1 was calculated. Data represent mean ± SE of n=4–6 animals per group. *P<0.05 (compared to untreated control); #P<0.05 (compared to sham-operated control).
