Table 1.
Canadian consensus definition of prostate cancer risk stratification
| RISK | DEFINITION |
|---|---|
| Low | ≤ T2a* and iPSA level ≤ 10 ng/mL and GS ≤ 6 |
| Intermediate | ≤ T2c* and iPSA level 10–20 ng/mL or GS ≤ 7 |
| High | ≥ T3a* or iPSA level ≥ 20 ng/mL or GS 8–10 |
GS—Gleason score, iPSA—initial prostate-specific antigen, PSA— prostate-specific antigen.
T1—tumour present, but not detectable clinically or with imaging (T1a—tumour was incidentally found in less than 5% of prostate tissue resected, T1b—tumour was incidentally found in greater than 5% of prostate tissue resected, T1c—tumour was found in a needle biopsy performed owing to an elevated serum PSA level); T2—the tumour can be palpated on examination, but has not spread outside the prostate (T2a—the tumour is in half or less than half of 1 of the prostate gland’s 2 lobes, T2b—the tumour is in more than half of 1 lobe, but not both, T2c—the tumour is in both lobes); T3—the tumour has spread through the prostatic capsule (T3a—the tumour has spread through the capsule on 1 or both sides, T3b—the tumour has invaded 1 or both seminal vesicles); T4—the tumour has invaded other nearby structures.