Table 5.
Genotype and allele frequencies of healthy individuals (n = 102) for all the polymorphisms studied.
Genotype frequency |
Allele frequency |
||||
---|---|---|---|---|---|
Wild type | Heterozygous | Homozygous | Wild type allele | Mutant allele | |
MDR1 (C3435T) |
26.4% (27) | 42.1% (43) | 31.4% (32) | 3435C = 0.475 | 3435T = 0.524 |
CYP2C19*2 (G681A) |
46% (47) | 37% (38) | 16.7% (17) | 681G = 0.647 | 681A = 0.352 |
CYP2C19*3 (G636A) |
100% (102) | 0 | 0 | 636G = 1.0 | – |
CYP2C19*17 (C806T) |
81.4% (83) | 16.7% (17) | 1.96% (2) | 806C = 0.897 | 806T = 0.102 |
P2Y12 (i-T744C) |
85.2% (87) | 11.8% (12) | 2.94% (3) | i744T = 0.911 | i744C = 0.088 |