Table 4.
NNRTI | Mean-squared error (SD)a | Classification accuracy (SD)b |
---|---|---|
Nevirapine | 0.26 (0.02) | 0.94 (0.01) |
Efavirenz | 0.15 (0.02) | 0.90 (0.02) |
Etravirine | 0.14 (0.02) | 0.83 (0.03) |
Rilpivirine | 0.17 (0.07) | 0.83 (0.06) |
SD, standard deviation.
aMean-squared error of 10 replicates of 5-fold cross-validation results of least squares regression using the 35 study-defined NNRTI-resistance mutations.
bClassification accuracy is defined as the proportion of phenotypes for which the classification categories of predicted and actual fold change were concordant (susceptible versus partial resistant versus resistant).