Table 4.

Prediction accuracy of least squares regression: mean-squared error and classification accuracy

NNRTI	Mean-squared error (SD)a	Classification accuracy (SD)b
Nevirapine	0.26 (0.02)	0.94 (0.01)
Efavirenz	0.15 (0.02)	0.90 (0.02)
Etravirine	0.14 (0.02)	0.83 (0.03)
Rilpivirine	0.17 (0.07)	0.83 (0.06)

SD, standard deviation.

^aMean-squared error of 10 replicates of 5-fold cross-validation results of least squares regression using the 35 study-defined NNRTI-resistance mutations.

^bClassification accuracy is defined as the proportion of phenotypes for which the classification categories of predicted and actual fold change were concordant (susceptible versus partial resistant versus resistant).