Table 2. List of the SNPs genotyped in this study with previously reported β coefficient.
SNP | Locus | β coefficient (SE) | P | Model | Allele associated with shorter LTL | References |
---|---|---|---|---|---|---|
rs2630578 | BICD1 | -0.604 (0.204) | 1.9 x 10-5 | Dominant | C | 16,18 |
rs2162440 | 18q12.2 | -0.106 (0.022) | 2.6 x 10-6 | Additive | G | 17,18 |
rs16847897 | TERC | -0.030 (0.008) | 9.33 x 10-5 | Additive | C | 18 |
rs12696304 | TERC | -0.034 (0.008) | 1.03 x 10-5 | Additive | G | 18,22 |
rs10936601 | TERC | 0,073 (0,034) | 0.034 | Additive | G | our unpublished GWAS (AETL) 2010 |
rs10786775 | OBFC1 | -0.120 (0.020) | 6.13 x 10-8 | Additive | C | 22 |
rs11591710 | OBFC1 | -0.110 (0.020) | 7.87 x 10-8 | Additive | A | 22 |
SE, standard error. B coefficient was directly copied from the publication and direction of the association will depend on the calculation.
The attention of the reader is attracted to the fact that all data were obtained using leucocytes telomeres length measurement for GWAS screen except our unpublished GWAS-AETL which was performed on aortic endothelial telomere length.