Table 6. Type II diabetes by TERC haplotype (UDACS compared to HIFMECH controls).
Haplotype | Freq in controls | Freq in T2D | OR (95% CI) | OR (95% CI) adjusted for LTL |
---|---|---|---|---|
CCG | 0.613 | 0.646 | 1.00 | 1.00 |
GTC | 0.259 | 0.199 | 0.74 (0.61-0.91) P=0.004 | 0.83 (0.69-1.01) P=0.07 |
GTG | 0.058 | 0.077 | 1.26 (0.89-1.80) P=0.20 | 1.36 (0.98-1.89) P=0.06 |
CCC | 0.054 | 0.064 | 1.12 (0.78-1.60) P=0.55 | 1.00 (0.72-1.39) P=1.00 |
Global p value | P=0.007 | P<0.0001 |
Order of SNPs is rs12696304 rs10936601 and rs16847897