Table I.
Overall score of γH2AX expression | |||||||||
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Group | n | Mean age (SD), years | Gender, M/F | −, n | +, n | ++, n | +++, n | %a | P-value |
1 CG | 56 | 53.6 (10.7) | 30/26 | 29 | 27 | 0 | 0 | 48.2 | |
2 IM | 53 | 54.3 (9.6) | 29/24 | 14 | 26 | 12 | 1 | 73.5 | <0.001b |
3 Dys | 47 | 55.1 (10.3) | 26/21 | 2 | 9 | 27 | 9 | 95.7 | <0.001b,c |
4 GC | 146 | 56.8 (14.1) | 96/50 | 15 | 57 | 50 | 24 | 89.7 | <0.001b; 0.011d |
Percentage of immunostaining.
vs. CG group;
vs. IM group;
vs. Dys group.
γH2AX, phosphorylated H2AX at Ser 139; M, male; F, female; CG, chronic gastritis; IM, intestinal metaplasia; Dys, dysplasia; GC, gastric cancer.