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GBS adherence to hBMEC is mediated by the interaction of the Srr protein and fibrinogen. GBS strains NCTC10/84 (A) or COH1 (B) or their Δsrr mutants were incubated with hBMEC, with or without fibrinogen pretreatment (20 μg/ml). Values represent percent (mean ± S.D.) of inoculum bound to the monolayers. *, p < 0.01.
