Table 1. Partial loss of function inflated alleles.
allele | mutation | location | muscle phenotype | midgut phenotype | wing phenotype | interalleleic complementation |
---|---|---|---|---|---|---|
ifC2B | D244 to N | ligand binding pocket | detachment from the ECM | strong | blister | ifC2B / ifSEF are viable |
if17 | D309 to N | cation coordination | weak cytoskeletal detachment | weak | none | if17 / ifC2B gives escapers |
if21 | A322 to T | GAP motif | weak cytoskeletal detachment | weak | none | if21 / ifC2B gives escapers |
if35 | G101 to S | cup tetrapeptide | weak cytoskeletal detachment | weak | none | none |
ifSEF | Not found | - | strong cytoskeletal detachment | none | none | ifC2B / ifSEF and if2B1 / ifSEF are viable |
if2B1 | Not found | - | none | strong | none | if2B1 / ifSEF are viable |