Table II. Selected DRM-associated proteins. Six DRM-associated proteins containing a signal peptide (SP) or a transmembrane domain (TM) or having a role in protein folding/trafficking were selected for the production of specific mouse immune sera. Protein regions expressed in bacteria are indicated.
| Gene ID | Parasite protein | SP | TM | Expected molecular weight (kDa) | Expressed region (amino acids) | Annotation |
|---|---|---|---|---|---|---|
| PF3D7_1104400 | PfK55 | + | − | 49 | 98–321 | Conserved protein, unknown function (ER retention signal KDEL) |
| PF3D7_1013300 | PfJ130 | + | 1C-term | 75 | 39–186 | Conserved protein, unknown function |
| PF3D7_1134000 | PfK351 | − | − | 73 | 195–496 | Heat shock protein hsp70 homologue |
| PF3D7_1222300 | PfL1070 | + | − | 95 | 27–416 | Endoplasmin homolog (ER retention signal SDEL) |
| PF3D7_0222100 | PfB985 | + | 2C-term | 27 | 73–176 | Pfmc-2TM family member 2.2 (PEXEL/HCT motif) |
| PF3D7_1420700 | PfN201 | + | 1C-term | 112 | 44–257 | Surface protein, Pf113 |