Table 1.
Some biochemical and biological activities of Naja kaouthia venom
| Parameters | Activity |
|---|---|
| LD50 | 0.148 mg/kg |
| PLA2 activity assay | 7.9±0.24Ψ |
| Direct hemolytic assay (100µg venom) | 1.4±0.51% |
| Indirect hemolytic assay ( 1µg venom) | 23.0 ±3% |
| Caseinolytic activity (100µg venom) | 0.14±0.02* |
| Creatine kinase (CK) ( 15µg i.m. injection) | 6.6±0.2 U/l |
| Lactate dehydrogenase (LDH) ( 15µg i.m. injection) | 26.3±2.3U/l |
| Minimum edema dose (MED) | 11.2±0.18 µg |
| Haemorraghic activity (up to 15µg) | NA |
*
Normal CK and LDH values are 0.63 U/l and 23.39 U/l respectively; Ψµmol of diheptanoyl Thiol-PC hydrolyzed/min/mg; *n moles of tyrosine formed/min; NA= No Activity. Results are mean ±SD (n=3)