Table 2.
Anticoagulant activity of Naja kaouthia venom on whole citrated blood. Results are expressed as mean ±SD of three experiments.
| Parameters | PBS | Crude venom (µg/ml) | ||
|---|---|---|---|---|
| 0.1 | 1.0 | 10 | ||
| Thromboelastometry analysis | ||||
| Coagulation time (CT) (s) | 503±10 | 634±15 | >1200 | >1200 |
| Clot formation time (CFT) (s) | 87±3 | 266±10 | NCF | NCF |
| Maximum clot firmness (MCF) (mm) | 65±2 | 61±1.3 | NCF | NCF |
| Sonoclot analysis | ||||
| Activated clotting time (ACT) (s) (range: 128–213) | 176±5.2 | 215±7.4 | 243±6.3 | 591±10 |
| Clot rate (CR)(range: 9.0–35) | 23±0.5 | 23±0.32 | 16±0.21 | 1.2±0.2 |
| Platelet function (range: 3–5) | 2.8±0.01 | 3.8±0.02 | 3.3±0.01 | 0 |
*
NCF: No clot formation, the results are expressed as mean ± SD