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TLR2 Agonist Activity (EC50 Values) Calculated From Dose-Response Curves.
| Compd | EC50 | R2 | |
|---|---|---|---|
| (nM) | Std. Error |
Value | |
| 3 | 56 | 1.1 | 0.99 |
| 8 | 25 | 1.1 | 0.99 |
| 9 | 78 | 1.1 | 0.99 |
| 10 | 20 | 1.0 | 0.99 |
| 11 | 204 | 1.3 | 0.97 |
| 12 | 39 | 1.1 | 0.98 |
| 13 | 34 | 1.2 | 0.98 |
| Pam2CSK4 | 3.7 | 1.4 | 0.96 |
| Pam3CSK4 | 23 | 1.5 | 0.94 |
