Skip to main content
. Author manuscript; available in PMC: 2013 Dec 13.
Published in final edited form as: J Med Chem. 2012 Nov 8;55(22):10.1021/jm301002f. doi: 10.1021/jm301002f

Table 4.

TLR2 Binding Affinity (Ki) Determined by Competition Binding Assays.

Compd TLR2 Expressing
Cell line
Ki R2
Value
(nM) Std.
Error
10 HEK-293/hTLR2 25 1.8 0.89
10 SU.86.86 91 1.4 0.95
12 SU.86.86 25 1.7 0.90
13 HEK-293/hTLR2 11 1.8 0.87
13 SU.86.86 67 2.3 0.78