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. 2013 Aug 1;20(e2):e281–e287. doi: 10.1136/amiajnl-2013-001861

Table 2.

Exposures and outcomes of HA-CDI cases as compared to matched controls

Exposure or outcome HA-CDI cases (n=362) HA-CDI controls (n=362) p Value HR or OR (95% CI)
Length of stay, median (IQR), days 20 (13–33) 9 (6–14) <0.001 0.34 (0.30 to 0.41)*
<0.001 0.33 (0.28 to 0.39)†
30-Day post-discharge mortality, no. (%) 80 (22) 42 (12) 0.05 1.48 (1.00 to 2.17)*
0.10 1.38 (0.94 to 2.04)†
High-risk antibacterial exposure, no. (%)‡,§ 240 (66) 124 (34) <0.001 3.77 (2.74 to 5.20)¶
Low-risk antibacterial exposure, no. (%)‡,§ 249 (69) 168 (46) <0.001 2.54 (1.86 to 3.49)¶
PPI or H2-blocker exposure, no. (%)‡,§ 297 (82) 265 (73) 0.006 1.67 (1.16 to 2.43)¶

*Unadjusted HR.

†Adjusted HR.

‡Medication POE data collected up to 24 h before diagnosis for cases, and for the first 48 h of healthcare exposure, for controls.

§Aggregate medication categories are defined in supplementary Table S2 (available online only).

¶OR.

HA-CDI, hospital-acquired C difficile; POE, provider order entry.