Table 1.
Early-onset Neonatal Sepsis | Late-onset Neonatal Sepsis | |
---|---|---|
Time of presentation | Within 24 hours of birth (range, to day 6 of life) | 4–5 weeks of age (range, 7–89 days) |
Clinical manifestations | Generalized sepsis, pneumonia, meningitis | Bacteremia without focus, meningitis, focal infection (septic arthritis, osteomyelitis, pneumonia, cellulitis, adenitis) |
Profound shock | Likely | Less likely |
Seizures in meningitis | Not likely | Likely |