Table 1.
Absolute lymphocyte count distribution
| Variable | Total (n=399) | ALC < 500 cells/μl (n=34) | ALC ≥ 500 cells/μl (n=365) | P-value* |
|---|---|---|---|---|
| Age at Diagnosis (%) | ||||
| 1 to 9 years | 293 | 21 (7.2) | 272 (92.8) | .107 |
| ≥ 10 years | 106 | 13 (12.3) | 93 (87.7) | |
| Leukocyte count (%) | ||||
| < 50 × 103/μL | 293 | 25 (8.5) | 268 (91.5) | .989 |
| ≥ 50 × 103/μL | 106 | 9 (8.5) | 97 (91.5) | |
| MRD (%) | ||||
| Negative (< 0.01%) | 318 | 19 (6.0) | 299 (94.0) | .005 |
| Positive (≥ 0.01%) | 77 | 13 (16.9) | 64 (83.1) | |
| Missing | 4 | 2 (50.0) | 2 (50.0) | |
| Lineage (%) | ||||
| B | 336 | 19 (5.7) | 317 (94.3) | < .001 |
| T | 63 | 15 (23.8) | 48 (76.2) | |
| Initial risk group (%) | ||||
| Low | 223 | 10 (4.5) | 213 (95.5) | .001 |
| Standard/High | 176 | 24 (13.6) | 152 (86.4) |
ALC, absolute lymphocyte count; MRD, minimal residual disease
*
Pearson’s chi-square test