Removal of fiber bundle core pattern. (a) Raw image of sponge stained with toluidine blue 0.25%, using the high resolution probe; (b) zoom on raw image showing honeycomb pattern of cores; (c,d,e) red, green and blue channels of image in (b), showing that cores can be resolved in each; (f) processed image following application of Gaussian filter; (g) zoom on processed image showing core pattern is no longer visible. Note that the brightness of the color channel images was adjusted for easier viewing. For presentation, the zoomed images were interpolated from 100x100 to 300x300 pixels by cubic interpolation.