Table 3.

Results of several 15-day strategic treatment interruption (abbreviated as STI above) plans. For each simulation, we report the first day of the 15-day treatment interruption, the maximum leukemia concentration that occurs after the interruption, the time required for the patient to achieve cytogenetic remission, and the time required for total cancer elimination (i.e., concentration < 10⁻¹⁰k/μL)

Treatment plan: First day of 15-day STI	Maximum leukemia concentration (k/μL) after interruption	Time until cytogenetic remission (days)	Time until total cancer elimination (days)
No STI	n/a	251	n/a
90	20.6 at t = 106	312	n/a
120	17.25 at t = 136	313	n/a
150	14.58 at t = 166	316	879
180	11.71 at t = 196	329	665
210	8.96 at t = 226	346	616
240	6.75 at t = 256	365	606
270	5.14 at t = 286	386	611
300	4.01 at t = 316	408	627
330	3.21 at t = 346	433	655
360	2.64 at t = 376	459	693
390	2.23 at t = 406	487	739