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. Author manuscript; available in PMC: 2013 Dec 13.
Published in final edited form as: Bull Math Biol. 2010 Jun 9;73(5):10.1007/s11538-010-9553-0. doi: 10.1007/s11538-010-9553-0

Table 4.

Results of several 30-day strategic treatment interruption (abbreviated as STI above) plans. For each simulation, we report the first day of the 30-day strategic treatment interruption, the maximum leukemia concentration that occurs after the interruption, the time required for the patient to achieve cytogenetic remission, and the time required for total cancer elimination (i.e., concentration < 10−10k/μL)

Treatment plan: First day of 30-day STI Maximum leukemia concentration (k/μL) after interruption Time until cytogenetic remission (days) Time until total cancer elimination (days)
No STI n/a 251 n/a
90 34.6 at t = 121 342 n/a
120 31.35 at t = 151 345 n/a
150 28.30 at t = 181 350 929
180 24.33 at t = 211 364 711
210 19.92 at t = 241 382 662
240 16.07 at t = 271 404 654
270 13.06 at t = 301 426 656
300 10.77 at t = 331 449 666
330 9.05 at t = 361 473 681
360 7.75 at t = 391 498 699
390 6.75 at t = 421 524 722