Table 1.
Reported cases of rectovaginal extragastrointestinal stromal tumor.
| First author, reference | No. of pts. | Age, years | Tumor size, cm | Treatment | No. of mitosis per 50 HPF | Necrosis | Cd117 | Cd34 | SMA | Ki-67 | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Nasu et al. (2004) | 1 | 54 | 8.5 | Surgery | 5–10 | + | + | + | + | N/A | Alive at 13 months |
| Ceballos et al. (2004) | 1 | 75 | 4.5 | Local excision | 12–15 | + | + | + | − | N/A | Recurrence at 7.5 years |
| Weppler and Gaertner (2005) | 1 | 66 | 8 | Imatinib | > 5 | − | + | + | − | N/A | N/A |
| Takano et al. (2006) | 1 | 38 | 7 | Surgery | 1–2 | N/A | + | + | + | N/A | Alive at 12 months |
| Lam et al. (2006) | 3 | 36 | 4 | N/A | 15 | − | + | + | − | N/A | Recurrence at 2 years |
| 48 | 6 | N/A | 12 | + | + | + | − | N/A | Recurrence at 10 years | ||
| 61 | 8 | N/A | 16 | − | + | + | − | N/A | N/A | ||
| Nagase et al. (2007) | 2 | 42 | 3.5 | Local excision | < 1 | + | + | + | − | 20–30 | Alive at 4 years |
| 66 | 5 | Surgery + imatinib | 2–3 | − | + | + | − | 30 | Alive at 6 months | ||
| Zhang et al. (2009) | 1 | 42 | 8 | Local excision | 10 | + | + | + | − | 3 | Alive, no time report |
| Muñoz (present case) | 1 | 15 | 2 | Surgery + TKIs* | 40 | + | + | − | − | N/A | Recurrence at 4 months, 12 months, and 18 months; DOD |
HPF, high-power field; N/A, not available; SMA, smooth muscle actin; TKIs, tyrosine kinase inhibitors.