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Kinetics of IRF1 and SOCS1 activation after IFNα-treatment of human tumor cell lines. Measurement of IRF1- and SOCS1-specific mRNA by qRT-PCR in M14 treated for 15 min, 3, 24 and 48 h with 250U/ml of IFNα. The results are expressed as the mean ± SEM of fold change of the copy number of the IFN-treated sample relative to the untreated control in three independent experiments.
