Table 2.

Comparative ratio of area under the concentration time curves AUC milk/AUC plasma of MLs in different species.

	Humans	Cattle	Buffaloes	Sheep	Goat	Camel
Ivermectin	0.6a	0.8 (Toutain et al., 1988)	–	1.0 (Bogan and McKellar, 1988) 2.5 ± 0.4 (Imperiale et al., 2004)	1.1 ± 0.2 (Alvinerie et al., 1993)	1.2 ± 0.4 (Oukessou et al., 1999)
Eprinomectin	–	0.1b (Alvinerie et al., 1999a,b,c)	0.8 ± 0.2 (Dupuy et al., 2008)	0.8 (Hodoscek et al., 2008)	0.1–0.2 (Dupuy et al., 2001)	2.9 ± 1.5 (Bengoumi et al., 2007)
Moxidectin	1.8 (Korth-Bradley et al., 2011)	–	5.0 ± 2.1 (Dupuy et al., 2008)	18.5 ± 1.2 (Imperiale et al., 2004)	7.5 (Carceles et al., 2001)c	4.2 ± 0.7 (Oukessou et al., 1999)

–: Not determined.

^aExtrapolation from data of Guzzo et al. (2002) and Ogbuokiri et al. (1993).

^b0.094 in zebu gobra (Bengone-Ndong et al., 2006).

^cEstimation.