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. 2013 Dec 13;8(12):e81634. doi: 10.1371/journal.pone.0081634

Figure 2. Evaluation of the anticonvulsant activity of ar-turmerone (AT) in the timed i.v.

Figure 2

PTZ infusion model.

Radar graphic depicts the doses of PTZ required to trigger seven characteristic behavioral events (ET: ear twitch, MT: myoclonic twitch, TT: tail twitch, FC: forelimb clonus, F: falling, THE: tonic hindlimb extension, D: death) after i.v. administration of AT at 1 and 20 mg/kg compared to vehicle-treated mice (control). Levetiracetam (LEV) 50 mg/kg was included as a positive control. Results are expressed as relative values compared to control (set as 100%). For reasons of clarity, mean values (± SD) and statistically significant differences are not shown here (for details see Table 2).