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. 2013 Dec 13;8(12):e83232. doi: 10.1371/journal.pone.0083232

Table 4. IV doses (mg/kg) at which the average subject would be expected to reach TEVs.

Schedule
Weekly Every 14 days Every 21 days
Cmax 2.3 3.3 3.8
Cmin 1.7 5.1 10.8
AUC 2.1 4.5 6.2

AUC, area under the plasma-concentration versus time curve; Cmax, maximum plasma concentration; Cmin, trough or minimum plasma concentration; IV, intravenous; TEVs, target exposure values.