Skip to main content
. 2013 Dec 13;8(12):e83480. doi: 10.1371/journal.pone.0083480

Table 2. Single- and multivariable proportional-hazard regression models of default from MDR-TB treatment.

Baseline variable Hazard ratio (95% CI) in univariate analysis P Hazard ratio (95% CI) in multivariable model P
Recent illicit drug use 2.78 (1.48, 5.22) 0.001 2.02 (1.04, 3.95) 0.04
Recent alcohol use 2.24 (1.22, 4.13) 0.01 2.11 (1.11, 4.02) 0.02
Steady employment (non-seasonal job, or student) 0.37 (0.17, 0.80) 0.01 0.41 (0.19, 0.90) 0.03
Married 0.42 (0.21, 0.84) 0.01
Formal dwelling 0.48 (0.25, 0.91) 0.03 0.38 (0.19, 0.78) 0.01
Age, per year of older age 0.98 ( 0.96, 1.00) 0.05 0.97 (0.94, 0.99) 0.01
Diagnosed at mobile clinic 2.00 (0.99, 4.07) 0.05
Recent tobacco use 2.02 (1.01, 4.05) 0.05
Town (non-farm) address 0.61 (0.37, 1.02) 0.06
Prior default from TB treatment 1.66 (0.95, 2.87) 0.07
BMI (per m2/kg) 0.94 (0.87, 1.01) 0.11
HIV infected 0.61 (0.32, 1.14) 0.12
Coloured ethnicity 1.72 (0.85, 3.49) 0.13 2.24 (1.03, 4.87) 0.04
Water, toilet, and electricity in patient’s dwelling 0.63 (0.33, 1.20) 0.17
Education (per year of schooling) 0.97 (0.90, 1.03) 0.30
Diabetes mellitus 0.36 (0.05, 2.69) 0.31
Female 0.82 (0.49, 1.36) 0.44
Initial sputum smear AFB positive at time of MDR-TB diagnosis 1.15 (0.67, 2.01) 0.60
Number of prior TB episodes (per prior episode) 0.94 (0.72, 1.22) 0.64
Current MDR-TB episode is patient’s first known TB episode 0.89 (0.40, 1.95) 0.76
Employed (any employment) 0.95 (0.55, 1.62) 0.84