Table 1. ATPase activity inhibition by CTS.
| Ouabain | Digitoxin | Bufalin | |
|---|---|---|---|
| MCF10A | 2013.65±50.0 | 1346.66±85.2 | 475.44±96.4 |
| 184D | 1185.3±81.3 | 2068.9±306.6 | 384.6±36.5 |
| 184A1 | 2461.9±220.2 | 1827.4±88.7 | 295.9±10.5 |
| MCF7 | 1975.1±32.7 | 1163.4±42.7 | 183.6±17.0 |
| MDAMB231 | 2123.9±44.2 | 1178.2±154.5 | 169.9±13.3 |
| MCF10CA1 | 2492.4±266.9 | 1482.1±73.8 | 164.6±9.1 |
IC50 values for CTS inhibition of ATPase activity in each cell type were calculated using the four-parameter logistic equation for CTS concentration (nM), and displayed as mean ± SE, n>3.