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. 2013 Dec 13;8(12):e84306. doi: 10.1371/journal.pone.0084306

Table 3. ERK and Src inhibitors do not sensitize tumor cells to CTS-induced cell death.

Treatment MCF7 MDAMB231
Control 100 ± 3.04 100 ± 17.7
500 nM Ouabain 89.56 ± 3.58 85.06 ± 12.69
5 µM ERK Inhibitor 104.10 ± 0.26 103.66 ± 10.42
10 µM Src Inhibitor 97.08 ± 2.26 86.60 ± 12.94
Ouabain + ERK Inhibitor 83.69 ± 1.72 77.60 ± 9.51
Ouabain + Src Inhibitor 81.14 ± 2.26 76.82 ± 12.15

Viability is displayed as the percentage of viable cells relative to untreated control; mean ± SE; n=3. Differences in viability from treatments with ouabain only compared to with ouabain plus inhibitor were not statistically significant (p>0.05).