Figure 3. Potent inhibitors of sEH elevate threshold of tonic seizure in the timed i.v. infusion test.

Consistent with the subcutaneous PTZ test both TUPS and TPPU, administered 1(vehicle n = 8, TPPU n = 6, TUPS n = 3, One Way ANOVA followed by Student Newman Keuls post hoc analysis *p = 0.026, # p = 0.005).