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. Author manuscript; available in PMC: 2013 Dec 14.
Published in final edited form as: Circ Heart Fail. 2013 May 24;6(4):10.1161/CIRCHEARTFAILURE.113.000277. doi: 10.1161/CIRCHEARTFAILURE.113.000277

Figure 6. Myocardial fibrosis and LVEDP in CAV patients according to the presence of collaterals.

Figure 6

A-C, Picrosirius red staining (red) demonstrating increased interstitial fibrosis in patients with CAV (B) compared to controls (A). Patients with CAV and collaterals (C) have reduced interstitial fibrosis compared to those without collaterals (B). D, Quantitation of interstitial fibrosis expressed as percent area of Picrosirius red staining. E, Increased LVEDP in CAV patients compared to controls. Patients coronary collaterals have reduced LVEDP compared to patients without collaterals. F-G, Linear regression analysis describing the relationship between myocardial fibrosis, microvascular density and LVEDP. * denotes p< 0.01 compared to controls, and ** denotes p< 0.01 compared to controls and patients with CAV lacking collaterals. Error bars indicate standard deviations.