Table 3.

Initial therapeutic management.

Score 1: Monitoring no cytokine

Outpatient clinical monitoring.

Blood count: every day for 6 days, then once a week for 2 months.

Score 2: Cytokines (curative)

G-CSF/KGF should be used as early as possible for 14–21 days.

EPO and stem cell factor questionable.

Symptomatic treatment for gastrointestinal damage.

If severe aplasia: protected environment.

Accidental radiation exposure is generally heterogeneous; some under-exposed/protected regions of bone marrow can give rise to endogenous hematopoietic recovery.

Score 3: Cytokines (until reappraisal of score)

Palliative/symptomatic treatment.

Re-evaluation during the first week based on laboratory or clinical.

Symptoms revealing irreversible organ damage/disfunction.