Table 2.

Indication for irradiation of the different target volumes after mastectomy and axillary clearance as well as for regional RT in the framework of BCT. Yes = evidence and generally accepted; Yes? = evidence but not generally accepted; No? = limited evidence, however advocated by some.

Risk category	Low	Intermediate	High
Thoracic wall	No?	Yes?	Yes
Supraclavicular	No?	Yes?	Yes
Internal mammary	No	Yes?	Yes?
Axilla	No	No	No

Reproduced with permission from Poortmans P. Educational review. Evidence based radiation oncology: breast cancer. Radiother Oncol 2007; 84: 84–101.