Table 2.

Results for pelvic Irradiation with IMRT in terms of local failure, disease free survival, and overall survival.

Author/year	n	Patients	Technique	Field	Planning target volume	Dose	Follow-up (median)	Local failure	Distant failure
Chen 200711	68	Cervix Adjuvant	4Fb vs IMRTa	Pelvic	na	50.4 Gy	14 m	EBRT: 4F 6% IMRT: 7%
Beriwal 200721	36	Cervix Ib2-IVa	IMRT	Pelvic + parac	CTV 0.5 + 1 cm	45 Gy	18 m
Kidd 201025	452	Cervix Ia-IVb PET CT staging	IMRT or 3Dc + HDR/LDR	PET positive Para, pelvic+ para	CTVd +7 mm	50.4 Gy	52 m	IMRT 8.1% 3Dce 10.4% p value ns	IMRT 15.6% 3Dc 24.6% p value ns
Chen 201120	109	Cervix IB2-IVA	IMRT + BTf	Pelvic	CTV + 0.7–1 cm	50.4–54 Gy	32 m	13.8% 3 years	22%
Hasselle 201122	111	Cervix I-IVA Radical and Adjuvant	IMRT + HDR – BTg	Pelvic	CTV + 0.7–1 cm	45 Gy	27 m	14%@ 3 years	17% @ 3years
Zhang 1224	58	Cervix I-II Adjuvant	IMRT – Para	Pelvic + Para	CTV +1 cm	50.4 Gy	34 m	3.4%	27%

^aIntensity modulated radiation therapy.

^bExternal beam radiotherapy 4 fields.

^cParaortic field.

^dClinical target volume.

^e3D conformal.

^fBrachytherapy.

^gHigh dose rate brachytherapy.