Table 2.

CXCR3 and its ligands in human disease and murine disease models

Disease/disease model	Receptor	Ligands
	CXCR3	CXCL9	CXCL10	CXCL11
Autoimmmune
Psoriasis		91, 92	91, 93	91
Sarcoid	94, 95	95, 96	94, 95	95, 96
Rheumatoid arthritis	21, 97–100	98	99, 101
Asthma	102, 103	102	102, 104–106	102
Atherosclerosis	107, 108	107	107, 109	107
Multiple sclerosis	110–116	111	110, 111, 117, 118
IBD	119		73
Idiopathic pulmonary fibrosis	120, 121		59, 60	122
Type 1 diabetes mellitus	70, 123		69, 123, 124
SLE	75, 125, 126	75	126, 127
Cigarette smoke injury/COPD	128–131	131	128, 131	131
Myocarditis	132		96, 133
Transplantation
Heart transplant	86, 134–137	41, 138	41, 139
Lung transplant	38, 140	38, 89	38, 89, 140	89
GVH	141, 142		142
Small bowel	72		72
Infections
Leprosy	143
Tuberculosis			144, 145
Influenza	146, 147		146, 147
Toxoplasma gondii			17, 148
Malaria	42, 78	42, 78	42, 78, 79, 149
Dengue	66		66, 150
Hepatitis B and C	151–153	151, 152	64, 151, 153, 154	151
Herpes simplex	22, 80	22, 80	22, 80, 155, 156
HIV-1	157	157	157–159	158
Leishmania	160	161	161, 162
Chlamydia trachomatis	163, 164		164
Lyme	165	166, 167	166, 167
West nile virus	67		67
Cancer
Renal	168	168	168	168
Colon			169, 170
Melanoma	171	171	171
Lymphoma	172–174		175
Breast	176		176

Abbreviations: COPD, chronic obstructive pulmonary disease; GVH, graft-versus-host; HIV, human immunodeficiency virus; IBD, inflammatory bowel disease; SLE, systemic lupus erythematosus.