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. 2013 Nov 27;2013:479628. doi: 10.1155/2013/479628

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Copyright © 2013 Hui Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of 0.7% ISO treatment on chemokine production, endothelial adhesion protein expression, and neutrophil recruitment in ZY-treated lung at 24 hrs. Levels of the following chemokines in BALF were measured by ELISA: (a) keratinocyte-derived chemokine (KC); (b) macrophage inhibitory protein-1α (MIP-1α); (c) macrophage inhibitory protein-2 (MIP-2); (d) monocyte chemoattractant protein-1 (MCP-1). The mRNA expression of the following endothelial adhesion molecules in lung tissue from all groups was measured by qPCR: (e) E-selectin; (f) ICAM-1; (g) VCAM-1. Lung MPO activity is shown in (h). The animals were treated as shown in Figure 1(a). Data represent mean ± SD (n = 10 mice per group). *P < 0.05 versus sham + vehicle; ^# P < 0.05 versus ZY + vehicle.