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. Author manuscript; available in PMC: 2013 Dec 15.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 May 2;33(7):10.1161/ATVBAHA.112.300922. doi: 10.1161/ATVBAHA.112.300922

Figure 5.

Figure 5

Statins upregulate small GTP-binding protein GDP dissociation stimulator (SmgGDS) in humans. A, Protein levels of SmgGDS in circulating human polymorphonuclear leukocytes. Crossover oral treatment with pravastatin (PRA, 20 mg/d for 2 weeks) or atorvastatin (ATOR, 20 mg/d for 2 weeks) significantly increased the SmgGDS level (n=20). B and C, Significant correlation between changes in SmgGDS and those in malondialdehyde (MDA)–low-density lipoprotein (LDL)-cholesterol. D and E, No correlation between changes in SmgGDS and those in LDL-cholesterol (n=20). Results are expressed as mean±SD.