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. 2013 Nov 28;2013:376216. doi: 10.1155/2013/376216

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Copyright © 2013 H. Ali and S. Dixit.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Light microphotographs of cross-sections of mouse skin. (a) Group 1: mouse received normal water demonstrating normal histological architecture,H&E, 400X. (b) Group 2: mouse topical exposure to DMBA + croton oil demonstrating damage ( → ) in dermal layer. H&E. 400X. (c) Group 3-mouse oral and topical exposure to palmatine for 16 weeks showing normal histological architecture. H&E. 400X. (d) Group 4: mouse oral (palmatine 100 mg/kg) and topical (DMBA + croton oil) exposure showing some normal histological architecture, H&E, 400X. Group 5: mouse oral (palmatine 200 mg/kg) and topical (DMBA + croton oil) exposure showing normal histological architecture,H&E, 400X.