TABLE 5.
MEDIAN BALF CHEMOKINE CONCENTRATIONS DURING DAD, AR, AND LB
| |
Healthy (pg/ml) | DAD |
AR |
LB |
|||
|---|---|---|---|---|---|---|---|
| pg/ml | P Value* | pg/ml | P Value* | pg/ml | P Value* | ||
| Sample size |
n = 325 |
n = 20 |
|
n = 70 |
|
n = 197 |
|
| No. of recipients |
n = 194 |
n = 18 |
|
n = 56 |
|
n = 129 |
|
| CXCL9 |
270.0 |
5234.6 |
0.0002 |
998.0 |
<0.0001 |
865.1 |
<0.0001 |
| CXCL10 |
115.3 |
206.8 |
0.0211 |
221.2 |
0.0112 |
212.7 |
0.0007 |
| CXCL11 | 81.1 | 95.5 | 0.0221 | 83.8 | 0.5370 | 83.7 | 0.0990 |
Definition of abbreviations: AR = acute rejection; BALF = bronchoalveolar lavage fluid; DAD = diffuse alveolar damage; LB = lymphocytic bronchiolitis.
Time from transplant (<3 mo vs. ≥3 mo) included as covariate.
*
Mixed-effects model with log-transformed chemokine levels.