TABLE 3.
METHYLATION PREVALENCE OF INDIVIDUAL GENES IN ALL LSC SUBJECTS, HISPANICS, AND NHWS
| Variable | Prevalence of Gene Methylation (%) |
P Value* | ||
|---|---|---|---|---|
| All Subjects (n = 1,540) | Hispanics (n = 341) | NHWs (n = 1,199) | ||
| P16 |
19.3 |
20.2 |
19.1 |
0.65 |
| MGMT |
26.2 |
26.3 |
26.1 |
0.94 |
| RASSF1A |
0.7 |
0.3 |
0.8 |
0.47† |
| DAPK |
16.9 |
20.2 |
15.9 |
0.06 |
| GATA4 |
37.4 |
43.9 |
35.5 |
0.005 |
| GATA5 |
15.4 |
20.2 |
14.1 |
0.006 |
| PAX5α |
14.5 |
13.2 |
14.9 |
0.43 |
| PAX5β |
8.4 |
8.8 |
8.3 |
0.80 |
| SULF2 |
35.8 |
44.2 |
33.4 |
0.0002 |
| PCDH20 |
36.9 |
44.2 |
34.9 |
0.0016 |
| DAL1 |
7.1 |
7.9 |
6.8 |
0.50 |
| JPH3 | 22.4 | 20.5 | 22.9 | 0.33 |
Definition of abbreviations: LSC = Lovelace Smokers cohort; NHWs = non-Hispanic whites.
*
Chi-square test compared the prevalence of gene methylation between 341 Hispanics and 1,199 NHWs.
†
Fisher exact test.