TABLE 5.

MULTIVARIATE ANALYSIS IDENTIFIED THAT NAA IN HISPANICS IS PROTECTIVE AGAINST GENE METHYLATION^*

Variable	OR (95% Confidence Interval)	P Value
Age, 10 yr	1.05 (0.92–1.19)	0.48
Male sex	1.11 (0.89–1.39)	0.33
Current smoker	0.81 (0.64–1.03)	0.086
Pack-years, 10	1.04 (0.98–1.10)	0.24
Chronic mucous hypersecretion	1.17 (0.95–1.45)	0.14
Body mass index ≥25	1.22 (0.97–1.54)	0.093
NAA, 0.24†	0.68 (0.48–0. 97)	0.032
African ancestry, 0.04‡	1.26 (0.97–1.62)	0.079

Definition of abbreviations: NAA = Native American ancestry; OR = odds ratio.

^*n = 341.

^†The 5th and 95th percentiles of NAA in Hispanics were 0.24 and 0.48. Thus, 0.24 was selected as a unit change of NAA in Hispanics to calculate the OR.

^‡The 5th and 95th percentiles of African ancestry in Hispanics were 0.008 and 0.048. Thus, 0.04 was selected as a unit change of African ancestry in Hispanics to calculate the OR.