Table 1B.

Estimated type-I errors (for OR = 1.00) and power (OR = 1.10, 1.25, 1.40 and 1.70) for different methods of addressing multiple comparisons in the eight marker LD block.

Odds ratio	1.00	1.10	1.25	1.40	1.70
Bonferroni	0.035	0.099	0.520	0.904	1.000
Maximum Z	0.050	0.128	0.576	0.925	1.000
combopt	0.051	0.184	0.688	0.958	1.000
combeq	0.049	0.090	0.266	0.515	0.869
combpair (markers 5 and 4)	0.051	0.121	0.442	0.774	0.986
combpair (markers 5 and 7)	0.050	0.061	0.114	0.192	0.328
SKAT	0.048	0.058	0.118	0.282	0.799

Marker 5 was assumed to be the causal locus.