Table 1.
Connectivity within the three identified patient clusters. The table summarizes the connectivity of the three clusters identified by Gaussian mixture modelling of the 41 individual dynamic causal models of patients with schizophrenia. Each row shows a particular model parameter. All parameter estimates are given in terms of mean ± standard error across the patients contained in each cluster. For a graphical interpretation of the means, see Fig. 5b.
| Model parameter | Cluster 1 (n = 9) | Cluster 2 (n = 24) | Cluster 3 (n = 7) |
|---|---|---|---|
| VC self-connection | − 1.000 ± 0.001 | − 0.994 ± 0.003 | − 1.001 ± 0.004 |
| VC → PC | 0.036 ± 0.022 | 0.070 ± 0.036 | 0.044 ± 0.025 |
| VC → DLPFC | 0.055 ± 0.029 | 0.044 ± 0.018 | 0.130 ± 0.068 |
| PC → VC | 0.017 ± 0.001 | 0.014 ± 0.004 | 0.017 ± 0.002 |
| PC self-connection | − 1.000 ± 0.000 | − 0.994 ± 0.004 | − 0.999 ± 0.001 |
| PC → DLPFC | 0.017 ± 0.001 | 0.014 ± 0.005 | 0.024 ± 0.007 |
| DLPFC → VC | 0.043 ± 0.026 | 0.021 ± 0.02 | 0.019 ± 0.004 |
| DLPFC → PC | 0.042 ± 0.024 | 0.034 ± 0.012 | 0.023 ± 0.008 |
| DLPFC self-connection | − 0.997 ± 0.003 | − 0.998 ± 0.001 | − 0.996 ± 0.003 |
| WM modulation of VC → DLPFC | 0.110 ± 0.227 | 0.124 ± 0.102 | 0.267 ± 0.135 |
| WM modulation of DLPFC → PC | 0.204 ± 0.191 | − 0.023 ± 0.017 | 0.071 ± 0.064 |
| Direct input to VC | 0.073 ± 0.043 | 0.074 ± 0.043 | 0.104 ± 0.020 |