Skip to main content
. 2013 Dec 16;4:193. doi: 10.3389/fendo.2013.00193

Figure 1.

Figure 1

Maximum-likelihood phylogeny of peptide hormone, Class A rhodopsin-like GPCRs in Cluster 1. The phylogeny presented is based on the seven transmembrane repeat region of proteins from Ae. aegypti, An. gambiae, C. quinquefasciatus, D. melanogaster, and D. mojavensis. Entries are identified by their VectorBase or FlyBase ID and accession number prefixes that indicate species: CG#, D. melanogaster; GI#, D. mojavensis; AAEL#, Ae. aegypti; AGAP#, An. gambiae; CPIJ#, C. quinquefasciatus. Assemblages and sub-assemblages are indicated to the right of the phylogeny. Each monophyletic clade of characterized or orphan GPCRs is highlighted with a different color and named after characterized ligands, where known. Clades containing the opsin and biogenic amine GPCRs have been collapsed. Nodes with likelihood scores >0.8 are denoted by thickened lines. Dots at nodes indicate level of support: 0.8–0.9 (yellow), 0.9–0.99 (blue), 1 (red); instances of split gene annotations are denoted by the inclusive range of accession numbers and marked with an asterisk. Isoforms of proteins were initially included in the tree but were removed if the two forms had a branch length of 0, and the tree was midpoint rooted.