Table 3. Summary of enriched gene expression profiles in each developmental stage.
Black text, stable enriched gene expression profile found into adulthood. Red text, transient enriched gene expression profiles that do not last into adulthood. N/P: Not present.
| Cell population | ED4 | ED6 | ED8 | ED10 | ED12 | P1 | Adult | ||
|---|---|---|---|---|---|---|---|---|---|
| Ventricle zone | EMX2 | EMX2 | EMX2 | EMX2 | EMX2 | EMX2 | EMX2 | ||
| PAX6 | PAX6 | PAX6 | PAX6 | PAX6 | PAX6 | PAX6 | |||
|
| |||||||||
| Pallium | Hippocampus | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | - | |
| LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | |||
| ER81 | ER81 | ER81 | ER81 | ||||||
| DLX1 | DLX1 | DLX1 | |||||||
|
| |||||||||
| Arcopallium | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | ||
| LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | LHX9 | |||
| ER81 | ER81 | ER81 | ER81 | ||||||
| DLX1 | DLX1 | - | |||||||
| NKX2.1 | |||||||||
|
| |||||||||
| Nidopallium | Caudal | N/P | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | |
| PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | ||||
| ER81 | - | - | - | - | |||||
| DLX1 | DLX1 | DLX1 | DLX1 | - | |||||
| NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | ||||||
| SEMA6A | SEMA6A | ||||||||
|
| |||||||||
| Anterior | N/P | N/P | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | COUP-TF2 | ||
| PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | |||||
| SEMA6A | SEMA6A | SEMA6A | SEMA6A | ||||||
| ER81 | ER81 | ER81 | - | ||||||
| NKX2.1 | NKX2.1 | NKX2.1 | |||||||
|
| |||||||||
| Hyperpallium | N/P | N/P | N/P | PPAPDC1A | PPAPDC1A | PPAPDC1A | PPAPDC1A | ||
| SEMA6A | SEMA6A | SEMA6A | SEMA6A | ||||||
|
| |||||||||
| Mesopallium | Dorsal | N/P | N/P | FOXP1 | FOXP1 | FOXP1 | FOXP1 | FOXP1 | |
| PPAPDC1A | PPAPDC1A | PPAPDC1A | - | ||||||
| ROR-ß | ROR-ß | ROR-ß | - | ||||||
| SEMA6A | SEMA6A | SEMA6A | - | ||||||
|
| |||||||||
| Ventral | N/P | N/P | N/P | FOXP1 | FOXP1 | FOXP1 | FOXP1 | ||
| ROR-ß | ROR-ß | ROR-ß | - | ||||||
|
| |||||||||
| Intercalated pallium | N/P | N/P | GRIN2D | GRIN2D | GRIN2D | GRIN2D | GRIN2D | ||
| ROR-ß | ROR-ß | ROR-ß | ROR-ß | ROR-ß | |||||
| NKX2.1 | |||||||||
|
| |||||||||
| Subpallium | Striatum | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | |
| DLX6 | DLX6 | DLX6 | DLX6 | DLX6 | DLX6 | ||||
| ER81 | ER81 | ER81 | ER81 | ER81 | - | ||||
| LHX8 | LHX8 | LHX8 | LHX8 | LHX8 | - | ||||
| DLX1 | - | - | - | - | - | ||||
| D1B | D1B | D1B | D1B | D1B | |||||
| FOXP1 | FOXP1 | FOXP1 | FOXP1 | FOXP1 | |||||
|
| |||||||||
| Pallidum | LHX8 | LHX8 | LHX8 | LHX8 | LHX8 | LHX8 | LHX8 | ||
| NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | NKX2.1 | |||
| DLX6 | DLX6 | DLX6 | DLX6 | DLX6 | DLX6 | - | |||
| DLX1 | DLX1 | - | - | - | - | - | |||
| ER81 | ER81 | ER81 | - | - | - | ||||
| GRIN2D | GRIN2D | GRIN2D | GRIN2D | GRIN2D | GRIN2D | ||||