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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Mol Biol Rep. 2013 Sep 7;40(10):10.1007/s11033-013-2656-6. doi: 10.1007/s11033-013-2656-6

Table 5.

Gene-cluster analysis for cumulative association of the less studied genetic variants in PLEKHA1/ARMS2/HTRA1 with AMD.

Data Fisher Simes TPMa
Meta-studies only <10−6 3.80×10−6 Un-weighted <10−5
Weighted <10−5
Single-studies only <10−6 2.80×10−6 Un-weighted <10−5
Weighted <10−5
All <10−6 3.13×10−6 Un-weighted <10−5
Weighted <10−5
a

Based on 100,000 simulations