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. Author manuscript; available in PMC: 2013 Dec 16.
Published in final edited form as: J Int Neuropsychol Soc. 2012 May 24;18(5):10.1017/S1355617712000689. doi: 10.1017/S1355617712000689

Table 3.

Neural activity during accurate retrieval of relational information and item information in normal control and aMCI participants

MNI Coordinates
Contrast Region of Activation Hemisphere BA x y z t k
Normal Control
  Relational > Item Inferior Parietal Lobule R 40 60 −28 20 6.68 148
Angular Gyrus L 39 −48 −62 14 6.33 69
Parahippocampal Cortex R 36 30 −34 −8 4.34 71
  Item > Relational Inferior Frontal Gyrus R 47 40 22 −6 4.34 53
Superior Frontal Gyrus R 10 30 60 8 4.18 45
aMCI
  Relational > Item Inferior Temporal Gyrus L 20 −50 −16 −22 6.03 26
Middle Frontal Gyrus L 9 −32 52 24 5.28 44
Superior Temporal Gyrus L 22 −46 −11 4 5.13 58
R 22 54 −8 2 5.13 27
  Item > Relational Inferior Frontal Gyrus R 45 60 22 16 6.00 59
Precuneus L 7 −18 −40 52 4.98 27
Superior Parietal Lobule L 7 −24 −58 50 4.23 20
Normal Control > aMCI
  Relational > Item Precuneus L 7 −16 −56 38 4.35 195
Posterior Cingulate R 31 18 −44 28 4.21 43
Parahippocampal Cortex R 36 30 −34 −10 4.12 50
Angular Gyrus L 39 −48 −62 16 4.10 79
  Item > Relational Inferior Frontal Gyrus R 47 32 22 −6 4.74 77
Superior Frontal Gyrus R 10 20 64 6 4.38 86
Inferior Frontal Gyrus R 47 30 12 −14 4.14 28
aMCI > Normal Control
  Relational > Item Superior Temporal Gyrus L 22 −50 −16 2 5.26 74
Supramarginal Gyrus R 40 64 −28 20 4.14 52
  Item > Relational Anterior Cingulate R 24 4 24 2 4.46 49
Inferior Frontal Gyrus R 45 60 22 18 4.39 64
Normal Control AND aMCI
  Relational > Item Superior Temporal Gyrus R 21 40 2 −12 7.80 49
  Item > Relational Middle Frontal Gyrus R 10 46 46 −12 6.33 32

Note. Regions significant at p < .005, k > 20. T = t-value; R = right; L = left; PHC = parahippocampal cortex; BA = approximate Brodmann area based on Montreal Neurological Institute coordinates.